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Treatment of Patients With Major Depressive Disorder With MK0869 (0869-073)

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ClinicalTrials.gov Identifier: NCT00042029
Recruitment Status : Completed
First Posted : July 23, 2002
Last Update Posted : May 5, 2017
Sponsor:
Information provided by (Responsible Party):
Merck Sharp & Dohme Corp.

Brief Summary:
A clinical study to determine the efficacy and safety of MK0869 in the treatment of depression.

Condition or disease Intervention/treatment Phase
Major Depressive Disorder Drug: MK0869, aprepitant Drug: Comparator: placebo Phase 3

Detailed Description:
The duration of treatment is 8 weeks.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 324 participants
Primary Purpose: Treatment
Official Title: A Double-Blind, Multicenter, Placebo-Controlled Study of MK0869 in the Treatment of Patients With Major Depressive Disorder
Actual Study Start Date : June 18, 2002
Primary Completion Date : October 3, 2003
Study Completion Date : October 3, 2003

Resource links provided by the National Library of Medicine

U.S. FDA Resources




Primary Outcome Measures :
  1. HAMD-17 total score; Tolerability

Secondary Outcome Measures :
  1. CGI-I Scale score; Sheehan Disability Scale


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Patients with Major Depressive Disorder

Publications:
Study Data/Documents: CSR Synopsis  This link exits the ClinicalTrials.gov site

Responsible Party: Merck Sharp & Dohme Corp.
ClinicalTrials.gov Identifier: NCT00042029     History of Changes
Other Study ID Numbers: 0869-073
Formally-8DL718
MK0869-073
2006_409
First Posted: July 23, 2002    Key Record Dates
Last Update Posted: May 5, 2017
Last Verified: May 2017

Additional relevant MeSH terms:
Disease
Depressive Disorder
Depression
Depressive Disorder, Major
Pathologic Processes
Mood Disorders
Mental Disorders
Behavioral Symptoms
Aprepitant
Fosaprepitant
Antiemetics
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Gastrointestinal Agents
Neurokinin-1 Receptor Antagonists
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action