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Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00041821
First Posted: July 22, 2002
Last Update Posted: March 23, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
  Purpose
This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called "problem buildings"), as well as in understanding the reflex mechanism of a response of the nose to irritants (e.g., nasal congestion).

Condition Intervention
Rhinitis, Allergic, Nonseasonal Procedure: Nasal irritation thresholds and irritant provocation

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Official Title: Individual Factors in Nasal Irritant Sensitivity

Resource links provided by NLM:


Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Estimated Enrollment: 64
Study Start Date: September 2000
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 69 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Non-smokers
  • 18-69 years of age
  • With or without allergic rhinitis (hay fever)
  • In good general health and with no prior history of asthma
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00041821


Locations
United States, California
Upper Airway Biology Laboratory
Richmond, California, United States, 94804
Sponsors and Collaborators
National Institute of Environmental Health Sciences (NIEHS)
  More Information

Additional Information:
Publications:
ClinicalTrials.gov Identifier: NCT00041821     History of Changes
Other Study ID Numbers: 10424-CP-001
First Submitted: July 18, 2002
First Posted: July 22, 2002
Last Update Posted: March 23, 2006
Last Verified: March 2006

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
rhinitis
irritation
trigeminal

Additional relevant MeSH terms:
Rhinitis
Rhinitis, Allergic
Rhinitis, Allergic, Perennial
Nose Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases