Paclitaxel in Treating Patients With Refractory or Recurrent Endometrial Cancer
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|ClinicalTrials.gov Identifier: NCT00022620|
Recruitment Status : Completed
First Posted : January 27, 2003
Last Update Posted : September 24, 2012
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of paclitaxel in treating patients who have refractory or recurrent endometrial cancer.
|Condition or disease||Intervention/treatment||Phase|
|Endometrial Cancer||Drug: paclitaxel||Phase 2|
- Determine the therapeutic activity of paclitaxel in patients with refractory or recurrent endometrial papillary carcinoma.
- Determine the objective response and duration of response in patients treated with this regimen.
- Determine the acute side effects of this regimen in these patients.
OUTLINE: This is a multicenter study.
Patients receive paclitaxel IV over 3 hours on day 1. Treatment repeats every 3 weeks in the absence of disease progression or unacceptable toxicity.
Patients are followed every 12 weeks.
PROJECTED ACCRUAL: Approximately 16-29 patients will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Masking:||None (Open Label)|
|Official Title:||Phase II Study On Paclitaxel In Recurrent Uterine Papillary Serous Carcinoma (UPSC)|
|Study Start Date :||June 2001|
|Primary Completion Date :||October 2002|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00022620
|Allgemeines Krankenhaus der Stadt Wien|
|Vienna, Austria, A-1090|
|Universitair Ziekenhuis Antwerpen|
|Edegem, Belgium, B-2650|
|Leuven, Belgium, B-3000|
|Ospedale Mauriziano Umberto I|
|Torino, Italy, 10128|
|Voghera (PV), Italy, 27058|
|Hospitais da Universidade de Coimbra (HUC)|
|Coimbra, Portugal, 3049|
|Hospital Universitasrio San Carlos|
|Madrid, Spain, 28040|
|Queen Elizabeth Hospital|
|Gateshead, England, United Kingdom, NE9 6SX|
|Study Chair:||Gerald Gitsch, MD||Allgemeines Krankenhaus - Universitatskliniken|