Preventing Chronic Whiplash Pain
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|ClinicalTrials.gov Identifier: NCT00021476|
Recruitment Status : Completed
First Posted : July 18, 2001
Last Update Posted : August 13, 2013
|Condition or disease||Intervention/treatment||Phase|
|Whiplash Injuries||Behavioral: Behavioral treatments Behavioral: Physical therapy||Phase 3|
More than 1.8 million people in the United States suffer from chronic pain and disability following motor vehicle accidents (MVAs) each year. The majority of these cases start with a relatively minor neck injury. The Quebec Task Force Study on Whiplash Associated Disorders (WAD) was created in 1989 to determine the clinical, public health, social, and financial determinants of WAD. Multiple studies have described the clinical features of WAD, which include neck, shoulder, arm, low back, and head pain; tinnitus; visual symptoms; dizziness; temporomandibular joint pain; and paraesthesias. Onset of these symptoms after the injury is usually delayed for several hours and worsens within 24 to 48 hours. Neck pain is the most frequent symptom, and between 14% and 42% of patients with WAD develop chronic neck pain symptoms. Studies suggest that the neck pain will either resolve in the first few months or persist indefinitely. One variable that may predict outcome after an MVA is the acute emotional response immediately after the MVA.
A severe emotional reaction accompanied by neck pain and stiffness after an MVA could lead an injured person to avoid subsequent physical activity through such mechanisms as fear avoidance and fear of reinjury. Research investigating the evolution of chronic pain due to musculoskeletal injury suggests that initial emotional reactivity, particularly fear of reinjury and subsequent activity avoidance, contributes significantly to unremitting pain and persistent disability. Research based on this model has shown that early interventions targeting normalization of excessive emotionality and restriction of activities associated with fear following injury effectively prevent chronic pain due to back injury. No previous study has sought to intervene during the first three months after an MVA with a behavioral and physical exercise program to encourage activity and discourage continued fear of movement, pain and disability.
This study consists of two primary components: (1) To compare the effectiveness of two anxiety-reduction treatments with standard care in reducing pain and activity limitations in patients with WADs 2 to 3 months following MVAs. (2) To test whether psychological responses to the initial trauma, such as fear avoidance, fear of injury, and negative affectivity, discriminate between symptomatic WAD patients and WAD sufferers whose symptoms had resolved 2 to 3 months post-MVA.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||300 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Preventing Chronic Whiplash Pain: Biobehavioral Approach|
|Study Start Date :||May 2001|
|Actual Primary Completion Date :||February 2007|
|Actual Study Completion Date :||February 2007|
- Pain [ Time Frame: Measured 3 months after the accident ]
- Functional activity [ Time Frame: Measured 3 months after the accident ]
- Mood [ Time Frame: Measured 3 months after the accident ]
- Fear avoidance [ Time Frame: Measured 3 months after the accident ]
- Range of motion/strength [ Time Frame: Measured 3 months after the accident ]
- Physical symptoms [ Time Frame: Measured 3 months after the accident ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00021476
|United States, Washington|
|University of Washington|
|Seattle, Washington, United States, 98195-6540|
|Principal Investigator:||Dennis C. Turk, PhD||University of Washington|