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Age-Related Changes in Stress Hormone Regulation

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ClinicalTrials.gov Identifier: NCT00018369
Recruitment Status : Completed
First Posted : July 5, 2001
Last Update Posted : January 21, 2009
Information provided by:

Study Description
Brief Summary:
Studies investigating physiological processes involved in aging-related deficits in regulation of stress hormone systems.

Condition or disease Phase
Physiological Processes Aging Phase 4

Study Design

Study Type : Observational
Time Perspective: Prospective
Official Title: Mechanism of Aging-Related Changes in (HPA) Hydrocortisone Corticotropin Feedback Function
Study Start Date : December 2000
Estimated Study Completion Date : April 2004

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hormones
U.S. FDA Resources

Groups and Cohorts

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Exclusion Criteria:

  • History of major psychiatric disorders,
  • Neurologic disorder affecting cognitive function,
  • Unstable medical problems,
  • Medications including antidepressants, neuroleptics, anxiolytics, CNS stimulants, narcotic analgesics, anti-convulsants,
  • Drugs effecting HPA axis function,
  • Vision and hearing deficits,
  • Undergoing major life event within one month or
  • Loss of family member within 6 months.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00018369

United States, Washington
VA Puget Sound Health Care System
Seattle, Washington, United States, 98108
Sponsors and Collaborators
VA Office of Research and Development
OverallOfficial: Richard Dorin
OverallOfficial: Elaine Peskind
OverallOfficial: Alan Schatzberg
OverallOfficial: Joseph Belanoff
More Information

ClinicalTrials.gov Identifier: NCT00018369     History of Changes
Other Study ID Numbers: AGCG-009-99F
First Posted: July 5, 2001    Key Record Dates
Last Update Posted: January 21, 2009
Last Verified: December 2004

Keywords provided by VA Office of Research and Development:
Hydrocortisone Corticotropin Feedback

Additional relevant MeSH terms:
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Cortisol succinate
Adrenocorticotropic Hormone
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs