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Age-Related Changes in Stress Hormone Regulation

This study has been completed.
Information provided by:
VA Office of Research and Development Identifier:
First received: July 3, 2001
Last updated: January 20, 2009
Last verified: December 2004
Studies investigating physiological processes involved in aging-related deficits in regulation of stress hormone systems.

Condition Phase
Physiological Processes Aging Phase 4

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Mechanism of Aging-Related Changes in (HPA) Hydrocortisone Corticotropin Feedback Function

Resource links provided by NLM:

Further study details as provided by VA Office of Research and Development:

Study Start Date: December 2000
Estimated Study Completion Date: April 2004

Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Exclusion Criteria:

  • History of major psychiatric disorders,
  • Neurologic disorder affecting cognitive function,
  • Unstable medical problems,
  • Medications including antidepressants, neuroleptics, anxiolytics, CNS stimulants, narcotic analgesics, anti-convulsants,
  • Drugs effecting HPA axis function,
  • Vision and hearing deficits,
  • Undergoing major life event within one month or
  • Loss of family member within 6 months.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00018369

United States, Washington
VA Puget Sound Health Care System
Seattle, Washington, United States, 98108
Sponsors and Collaborators
VA Office of Research and Development
OverallOfficial: Richard Dorin
OverallOfficial: Elaine Peskind
OverallOfficial: Alan Schatzberg
OverallOfficial: Joseph Belanoff
  More Information Identifier: NCT00018369     History of Changes
Other Study ID Numbers: AGCG-009-99F
Study First Received: July 3, 2001
Last Updated: January 20, 2009

Keywords provided by VA Office of Research and Development:
Hydrocortisone Corticotropin Feedback

Additional relevant MeSH terms:
Hydrocortisone 17-butyrate 21-propionate
Cortisol succinate
Hydrocortisone acetate
Adrenocorticotropic Hormone
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs processed this record on June 23, 2017