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Age-Related Changes in Stress Hormone Regulation

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00018369
First Posted: July 5, 2001
Last Update Posted: January 21, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
VA Office of Research and Development
  Purpose
Studies investigating physiological processes involved in aging-related deficits in regulation of stress hormone systems.

Condition Phase
Physiological Processes Aging Phase 4

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Mechanism of Aging-Related Changes in (HPA) Hydrocortisone Corticotropin Feedback Function

Resource links provided by NLM:


Further study details as provided by VA Office of Research and Development:

Study Start Date: December 2000
Estimated Study Completion Date: April 2004
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Exclusion Criteria:

  • History of major psychiatric disorders,
  • Neurologic disorder affecting cognitive function,
  • Unstable medical problems,
  • Medications including antidepressants, neuroleptics, anxiolytics, CNS stimulants, narcotic analgesics, anti-convulsants,
  • Drugs effecting HPA axis function,
  • Vision and hearing deficits,
  • Undergoing major life event within one month or
  • Loss of family member within 6 months.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00018369


Locations
United States, Washington
VA Puget Sound Health Care System
Seattle, Washington, United States, 98108
Sponsors and Collaborators
VA Office of Research and Development
Investigators
OverallOfficial: Richard Dorin
OverallOfficial: Elaine Peskind
OverallOfficial: Alan Schatzberg
OverallOfficial: Joseph Belanoff
  More Information

ClinicalTrials.gov Identifier: NCT00018369     History of Changes
Other Study ID Numbers: AGCG-009-99F
First Submitted: July 3, 2001
First Posted: July 5, 2001
Last Update Posted: January 21, 2009
Last Verified: December 2004

Keywords provided by VA Office of Research and Development:
Aging
Hydrocortisone Corticotropin Feedback

Additional relevant MeSH terms:
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Cortisol succinate
Hydrocortisone
Adrenocorticotropic Hormone
Anti-Inflammatory Agents
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs