Age-Related Changes in Stress Hormone Regulation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00018369
Recruitment Status : Completed
First Posted : July 5, 2001
Last Update Posted : January 21, 2009
Information provided by:
VA Office of Research and Development

Brief Summary:
Studies investigating physiological processes involved in aging-related deficits in regulation of stress hormone systems.

Condition or disease
Physiological Processes Aging

Study Type : Observational
Time Perspective: Prospective
Official Title: Mechanism of Aging-Related Changes in (HPA) Hydrocortisone Corticotropin Feedback Function
Study Start Date : December 2000
Study Completion Date : April 2004

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Exclusion Criteria:

  • History of major psychiatric disorders,
  • Neurologic disorder affecting cognitive function,
  • Unstable medical problems,
  • Medications including antidepressants, neuroleptics, anxiolytics, CNS stimulants, narcotic analgesics, anti-convulsants,
  • Drugs effecting HPA axis function,
  • Vision and hearing deficits,
  • Undergoing major life event within one month or
  • Loss of family member within 6 months.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00018369

United States, Washington
VA Puget Sound Health Care System
Seattle, Washington, United States, 98108
Sponsors and Collaborators
VA Office of Research and Development
OverallOfficial: Richard Dorin
OverallOfficial: Elaine Peskind
OverallOfficial: Alan Schatzberg
OverallOfficial: Joseph Belanoff Identifier: NCT00018369     History of Changes
Other Study ID Numbers: AGCG-009-99F
First Posted: July 5, 2001    Key Record Dates
Last Update Posted: January 21, 2009
Last Verified: December 2004

Keywords provided by VA Office of Research and Development:
Hydrocortisone Corticotropin Feedback

Additional relevant MeSH terms:
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Cortisol succinate
Adrenocorticotropic Hormone
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs