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Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00018304
First Posted: July 5, 2001
Last Update Posted: January 21, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
VA Office of Research and Development
  Purpose
The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements in metabolic insulin action. In addition, the study will track whether these improvements are related to changes in blood pressure.

Condition Phase
Hypertension Phase 1

Study Type: Observational
Official Title: Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

Resource links provided by NLM:


Further study details as provided by VA Office of Research and Development:

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
Age 50 - 75 years, elevated blood pressure, BMI greater than 25 but less than 40 kg/m2
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00018304


Locations
United States, Minnesota
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Sponsors and Collaborators
VA Office of Research and Development
Investigators
OverallOfficial: Arthur Leon, M.D.
OverallOfficial: Alan Blank, M.D.
  More Information

ClinicalTrials.gov Identifier: NCT00018304     History of Changes
Other Study ID Numbers: AGCG-005-98S
First Submitted: July 3, 2001
First Posted: July 5, 2001
Last Update Posted: January 21, 2009
Last Verified: December 2004

Keywords provided by VA Office of Research and Development:
blood pressure
insulin sensitivity
blood flow

Additional relevant MeSH terms:
Insulin, Globin Zinc
Insulin
Hypoglycemic Agents
Physiological Effects of Drugs