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Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11

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ClinicalTrials.gov Identifier: NCT00015301
Recruitment Status : Completed
First Posted : April 18, 2001
Last Update Posted : February 24, 2017
Sponsor:
Collaborator:
Information provided by:

Study Description
Brief Summary:
The purpose of this study is to evaluate PET methodology to study in vivo synaptic dopamine release.

Condition or disease Intervention/treatment Phase
Cocaine-Related Disorders Substance-Related Disorders Drug: Methylphenidate Phase 4

Detailed Description:
The objective of this study is to evaluate PET methodology to study in vivo synaptic dopamine release.

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 0 participants
Masking: Double
Primary Purpose: Diagnostic
Official Title: Methylphenidate Raclopride PET Test
Actual Study Start Date : December 2003
Primary Completion Date : June 2005
Study Completion Date : August 2005

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions


Outcome Measures

Primary Outcome Measures :
  1. Dopamine receptor availability

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Healthy normals

Exclusion Criteria:

History of head trauma or loss of consciousness. Significant medical history. History of seizures.

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00015301


Locations
United States, New York
New York MDRU
New York, New York, United States, 10010
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
New York MDRU
Investigators
Principal Investigator: John Rotrosen, M.D. New York MDRU
More Information

ClinicalTrials.gov Identifier: NCT00015301     History of Changes
Other Study ID Numbers: NIDA-5-0013-11
Y01-5-0013-11
First Posted: April 18, 2001    Key Record Dates
Last Update Posted: February 24, 2017
Last Verified: December 2002

Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
Disease
Substance-Related Disorders
Cocaine-Related Disorders
Pathologic Processes
Chemically-Induced Disorders
Mental Disorders
Methylphenidate
Raclopride
Central Nervous System Stimulants
Physiological Effects of Drugs
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents
Antipsychotic Agents
Tranquilizing Agents
Central Nervous System Depressants
Psychotropic Drugs
Dopamine Antagonists