Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Disorder - 5

This study has been completed.
Cincinnati MDRU
Information provided by:
National Institute on Drug Abuse (NIDA) Identifier:
First received: April 18, 2001
Last updated: June 2, 2015
Last verified: October 2012
The purpose of this study is the use of Methylphenidate in the treatment of cocaine dependence and Attention Deficit Hyperactivity Disorder (ADHD) comorbidity.

Condition Intervention Phase
Cocaine-Related Disorders
Substance-Related Disorders
Drug: Methylphenidate
Phase 2

Study Type: Interventional
Study Design: Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Methyphendidate in the Treatment of Cocaine Dependent Patients With Adult ADHD

Resource links provided by NLM:

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Cocaine use
  • Methylphenidate retention
  • Safety assessments
  • Psychosocial counseling sessions

Estimated Enrollment: 0
Study Start Date: June 1997
Detailed Description:
The objective of this study is to determine the safety and efficacy of methylphenidate in a population of patients who are cocaine dependent and suffer from attention deficit hyperactivity disorder.

Ages Eligible for Study:   21 Years to 50 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Cocaine-dependent. Meets the DSM-IV criteria for ADHD. Actively using cocaine within the past 30 days of screening.

Exclusion Criteria:

Symptoms of AIDS. Significant medical disorder. DSM-IV criteria for any substance other than cocaine, alcohol, nicotine, marijuana, caffeine. Requires detoxification from ETOH or benzos. History of seizures.

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Please refer to this study by its identifier: NCT00015223

United States, Ohio
Cincinnati MDRU
Cincinnati, Ohio, United States
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Cincinnati MDRU
Principal Investigator: Gene Somoza, M.D. U of Cincinnati
  More Information

No publications provided Identifier: NCT00015223     History of Changes
Other Study ID Numbers: NIDA-5-0013-5  Y01-5-0013-5 
Study First Received: April 18, 2001
Last Updated: June 2, 2015
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Cocaine-Related Disorders
Substance-Related Disorders
Attention Deficit and Disruptive Behavior Disorders
Chemically-Induced Disorders
Mental Disorders
Mental Disorders Diagnosed in Childhood
Pathologic Processes
Central Nervous System Agents
Central Nervous System Stimulants
Dopamine Agents
Dopamine Uptake Inhibitors
Molecular Mechanisms of Pharmacological Action
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses processed this record on February 08, 2016