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Environmental Contaminants and Infant Development

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ClinicalTrials.gov Identifier: NCT00013858
Recruitment Status : Completed
First Posted : April 3, 2001
Last Update Posted : April 14, 2015
Information provided by:

Study Description
Brief Summary:
This study is designed to examine the effects of prenatal exposure to environmental contaminants on cognitive and behavioral development and physical growth in two groups of Inuit infants-one in Northern Quebec; the other in Greenland.

Condition or disease
Mercury Poisoning Lead Poisoning

Detailed Description:
Due to prevailing weather patterns and ocean currents, certain environmental contaminants are transported to the Arctic region. The Inuit are among the most heavily exposed populations on earth due to the prevalence of these contaminants in traditional foods that comprise a large portion of their diet. The contaminants assessed in this study include polychlorinated biphenyls (PCBs), methylmercury, selenium, organochlorine pesticides, and lead. These contaminants are measured in umbilical cord blood samples obtained at birth, milk samples obtained from breast-feeding mothers and, in the case of mercury, hair samples obtained from the mothers. Omega-3 and omega-6 fatty acids are also assessed in these samples to examine the degree to which these nutrients may protect against adverse effects attributable to these contaminants.

Study Design

Study Type : Observational
Estimated Enrollment : 280 participants
Time Perspective: Prospective
Study Start Date : January 1997
Primary Completion Date : August 2011
Study Completion Date : August 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Mercury
U.S. FDA Resources

Groups and Cohorts

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   up to 1 Day   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
infant born during recruitment period to a mother who is a resident of Povungnituk, Inukjuak, and Kuujjuarapik, Quebec or Nuuk, Greenland
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00013858

Canada, Quebec
Public Health Centre of Quebec
Beauport, Quebec, Canada
Sponsors and Collaborators
National Institute of Environmental Health Sciences (NIEHS)
Indian and Northern Affairs, Canada
Health Canada
Danish Institute for Public Health
More Information

ClinicalTrials.gov Identifier: NCT00013858     History of Changes
Other Study ID Numbers: 7902-CP-001
First Posted: April 3, 2001    Key Record Dates
Last Update Posted: April 14, 2015
Last Verified: April 2015

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
fish consumption

Additional relevant MeSH terms:
Lead Poisoning
Mercury Poisoning
Chemically-Induced Disorders