We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Exposure, Dose, Body Burden and Health Effects of Lead

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00013819
First Posted: March 30, 2001
Last Update Posted: April 14, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
  Purpose
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.

Condition
Lead Poisoning

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Exposure, Dose, Body Burden and Health Effects of Lead

Resource links provided by NLM:


Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Estimated Enrollment: 944
Study Start Date: February 1997
Study Completion Date: February 2001
Primary Completion Date: February 2001 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   17 Years to 70 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Lead workers in South Korea in one of 26 specific lead-using facilities.

Population controls in South Korea.

  Contacts and Locations
No Contacts or Locations Provided
  More Information

ClinicalTrials.gov Identifier: NCT00013819     History of Changes
Other Study ID Numbers: 7198-CP-001
First Submitted: March 29, 2001
First Posted: March 30, 2001
Last Update Posted: April 14, 2015
Last Verified: April 2015

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
lead poisoning
central nervous system
peripheral nervous system
occupational health
genetic susceptibility

Additional relevant MeSH terms:
Poisoning
Lead Poisoning
Chemically-Induced Disorders