Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases
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|ClinicalTrials.gov Identifier: NCT00007007|
Recruitment Status : Completed
First Posted : March 8, 2004
Last Update Posted : March 27, 2015
RATIONALE: Assessment of patients undergoing radiation therapy may help to determine the effects of the treatment and may help improve cancer treatment.
PURPOSE: This clinical trial is studying the memory skills in patients receiving radiation therapy for brain metastases.
|Condition or disease||Intervention/treatment||Phase|
|Cognitive/Functional Effects Metastatic Cancer Radiation Toxicity||Procedure: management of therapy complications Procedure: quality-of-life assessment||Not Applicable|
OBJECTIVES: I. Determine the feasibility of performing a test battery consisting of five neurocognitive measures and a quality of life instrument following radiotherapy in patients with brain metastases.
OUTLINE: Patients undergo radiotherapy 5 days a week for 3 weeks. Quality of life and neurocognitive function is assessed before study, at completion of radiotherapy, and at 1 month after completion of radiotherapy. Patients are followed at 1 month.
PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study over 5 months.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||59 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Feasibility Study of Neurocognitive Evaluation in Patients Treated for Brain Metastases|
|Study Start Date :||November 2000|
|Actual Primary Completion Date :||December 2004|
|Actual Study Completion Date :||December 2004|
Experimental: Whole brain radiation therapy + neurocognitive assessments
Whole brain radiation therapy (WBRT) with neurocognitive assessments done pre and post WBRT.
Procedure: management of therapy complications
Procedure: quality-of-life assessment
- Feasibility of performing a test battery of neurocognitive and quality of life measures [ Time Frame: From registration to one month post radiation therapy ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00007007
Show 241 Study Locations
|Study Chair:||William F. Regine, MD||Lucille P. Markey Cancer Center at University of Kentucky|