Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
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|ClinicalTrials.gov Identifier: NCT00006864|
Recruitment Status : Completed
First Posted : June 2, 2003
Last Update Posted : January 9, 2014
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill kidney cancer cells.
PURPOSE: Phase IV trial to study the effectiveness of interleukin-2 in treating patients who have metastatic kidney cancer.
|Condition or disease||Intervention/treatment||Phase|
|Kidney Cancer||Biological: aldesleukin||Phase 4|
- Determine the overall response rate, complete and partial response rates, and duration of response in patients with metastatic renal cell carcinoma treated with low-dose interleukin-2.
- Determine the overall survival, one-year progression-free survival, and two-year progression-free survival in patients treated with this regimen.
- Determine the incidence of adverse events in these patients.
OUTLINE: This is a multicenter study.
Patients receive low-dose interleukin-2 subcutaneously 5 days a week for 6 weeks. Courses repeat every 9 weeks for at least 2 courses in the absence of disease progression or unacceptable toxicity.
Patients are followed every 3 months for 2 years.
PROJECTED ACCRUAL: A total of 464 patients will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Interleukin-2 In An Alternative Dose (The Iliad Trial): Treatment Of Patients With Metastatic Renal Cell Carcinoma With Low Dose Proleukin|
|Study Start Date :||July 2000|
|Actual Primary Completion Date :||July 2007|
|Actual Study Completion Date :||July 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00006864
|United States, Connecticut|
|Northwestern Connecticut Oncology-Hematology Associates|
|Torrington, Connecticut, United States, 06790|
|United States, Ohio|
|Ireland Cancer Center|
|Cleveland, Ohio, United States, 44106-5065|
|Study Chair:||Cindy Connell, MD, PhD||University Hospitals Seidman Cancer Center|