This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft Nephropathy

This study has been completed.
Information provided by:
National Center for Research Resources (NCRR) Identifier:
First received: October 4, 2000
Last updated: June 23, 2005
Last verified: December 2003
This study is intended to help doctors learn about the relationships between specific genetic makeup (gene markers) and the development of chronic rejection. This study is being done to see if there is a relationship between genetic patterns and the development of Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how genetic differences between people determine their response to a drug or a disease by storing a small blood sample in a special "bank". This sample may be tested at some point in the future in an attempt to better understand the factors that may influence rejection, transplantation outcomes and transplant success rates.

Kidney Disease

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by National Center for Research Resources (NCRR):


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All subjects must be recipients of a renal allograft.
  • Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy (CAN).
  • Control subjects must not have evidence of CAN.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00006328

United States, Michigan
Univ. of Michigan Health System
Ann Arbor, Michigan, United States, 48109-0391,
Sponsors and Collaborators
National Center for Research Resources (NCRR)
  More Information Identifier: NCT00006328     History of Changes
Other Study ID Numbers: NCRR-M01RR00042-1678
M01RR000042 ( U.S. NIH Grant/Contract )
Study First Received: October 4, 2000
Last Updated: June 23, 2005

Keywords provided by National Center for Research Resources (NCRR):
Chronic Allograft Nephropathy (CAN)
Transplantation immunology
Graft Rejection

Additional relevant MeSH terms:
Kidney Diseases
Urologic Diseases processed this record on August 17, 2017