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Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft Nephropathy

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00006328
First Posted: October 5, 2000
Last Update Posted: December 9, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Center for Research Resources (NCRR)
  Purpose
This study is intended to help doctors learn about the relationships between specific genetic makeup (gene markers) and the development of chronic rejection. This study is being done to see if there is a relationship between genetic patterns and the development of Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how genetic differences between people determine their response to a drug or a disease by storing a small blood sample in a special "bank". This sample may be tested at some point in the future in an attempt to better understand the factors that may influence rejection, transplantation outcomes and transplant success rates.

Condition
Kidney Disease

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Retrospective

Resource links provided by NLM:


Further study details as provided by National Center for Research Resources (NCRR):

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • All subjects must be recipients of a renal allograft.
  • Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy (CAN).
  • Control subjects must not have evidence of CAN.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00006328


Locations
United States, Michigan
Univ. of Michigan Health System
Ann Arbor, Michigan, United States, 48109-0391,
Sponsors and Collaborators
National Center for Research Resources (NCRR)
  More Information

ClinicalTrials.gov Identifier: NCT00006328     History of Changes
Other Study ID Numbers: NCRR-M01RR00042-1678
M01RR000042 ( U.S. NIH Grant/Contract )
First Submitted: October 4, 2000
First Posted: October 5, 2000
Last Update Posted: December 9, 2005
Last Verified: December 2003

Keywords provided by National Center for Research Resources (NCRR):
Chronic Allograft Nephropathy (CAN)
Transplantation immunology
Genetics
Graft Rejection

Additional relevant MeSH terms:
Kidney Diseases
Urologic Diseases