This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients

This study has been completed.
Information provided by:
National Center for Research Resources (NCRR) Identifier:
First received: September 7, 2000
Last updated: June 23, 2005
Last verified: December 2003
Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline. The declines in muscle mass associated with aging may be related to alterations in specific kinds of growth factors in the muscle. Elderly hip fracture patients often have significant decreases in muscle mass. The purpose of this study is to investigate whether an exercise program can induce changes in muscle growth factors that are associated with increases in muscle mass and strength in elderly hip fracture patients.

Condition Intervention
Hip Fractures Muscular Atrophy Behavioral: Exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by National Center for Research Resources (NCRR):


Ages Eligible for Study:   65 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Enrollment in HSC protocol #97-0695 "Rehabilitation Intensification Post Hip Fracture"
  • Community-dwelling
  • Hip fracture within 16 weeks of the screening assessment for protocol 97-0695
  • Persistent mobility and/or ADL impairments, but independent in ambulation
  • Modified Physical Performance Test (PPT) score between 12 and 28
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00006194

United States, Missouri
Washington University
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
National Center for Research Resources (NCRR)
  More Information Identifier: NCT00006194     History of Changes
Other Study ID Numbers: NCRR-M01RR00036-0764
M01RR000036 ( U.S. NIH Grant/Contract )
Study First Received: September 7, 2000
Last Updated: June 23, 2005

Keywords provided by National Center for Research Resources (NCRR):

Additional relevant MeSH terms:
Fractures, Bone
Hip Fractures
Muscular Atrophy
Wounds and Injuries
Pathological Conditions, Anatomical
Femoral Fractures
Hip Injuries
Leg Injuries
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on August 18, 2017