Salt Sensitivity, Cardiovascular and Metabolic Disease
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|ClinicalTrials.gov Identifier: NCT00005489|
Recruitment Status : Completed
First Posted : May 26, 2000
Last Update Posted : December 30, 2015
|Condition or disease|
|Cardiovascular Diseases Heart Diseases Hypertension Angina Pectoris Cerebrovascular Accident Myocardial Infarction Diabetes Mellitus Heart Failure, Congestive Heart Failure|
Approximately 498 of 750 normal and hypertensive subjects who were carefully characterized in terms of blood pressure response to salt loading and depletion in the late 1970s were re-examined to identify physiological factors contributing to salt-sensitivity of blood pressure. This helped to confirm preliminary observations suggesting that salt sensitivity in normotensive subjects predicted the subsequent development of hypertension with aging. In addition, longitudinal observations in hypertensive patients and in normotensives helped to determine whether salt-sensitivity or salt-resistance of blood pressure were associated with differences in the risk for development of specific forms of cardiovascular disease (stroke, angina, myocardial infarction, congestive heart failure), renal and metabolic (diabetes mellitus) disorders.
|Study Type :||Observational|
|Study Start Date :||January 1998|
|Study Completion Date :||December 2001|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00005489
|OverallOfficial:||Myron Weinberger||Indiana University-Purdue University|