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Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children

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ClinicalTrials.gov Identifier: NCT00005323
Recruitment Status : Completed
First Posted : May 26, 2000
Last Update Posted : February 18, 2016
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)

Brief Summary:
To conduct an epidemiologic study of persistent pulmonary hypertension of the newborn ( PPHN) infant.

Condition or disease
Lung Diseases Cardiovascular Diseases Defect, Congenital Heart Heart Diseases Persistent Fetal Circulation Syndrome

Detailed Description:

BACKGROUND:

The study on the epidemiology of persistent pulmonary hypertension of the newborn (PPHN) was a subproject within a Specialized Center of Research (SCOR) in Lung Biology and Diseases in Infants and Children. The SCOR and its subproject were awarded in December, 1991. Dollars were estimated at 20 percent of total center dollars.

DESIGN NARRATIVE:

Data from a previous study of PPHN were analyzed. The objectives were to: identify the effects of a variety of potentially adverse prenatal exposures from interview data; formulate multi-variate models of risk of PPHN to determine if smoking or use of prostaglandin inhibitors increased the risk of PPHN; explore associations of PPHN with history of illicit drug use and maternal hypoxia; examine the relationships of postnatal care and perinatal risk factors on the incidence and outcome of PPHN; test the relationships of PPHN to the biochemical presence of nicotine and drugs in neonatal urine.

The study completion date listed in this record was obtained from the "End Date" entered in the Protocol Registration and Results System (PRS) record.


Study Type : Observational
Study Start Date : December 1991
Study Completion Date : November 1996




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Ages Eligible for Study:   up to 100 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria
No eligibility criteria

Publications:
ClinicalTrials.gov Identifier: NCT00005323     History of Changes
Other Study ID Numbers: 4104
P50HL046491 ( U.S. NIH Grant/Contract )
First Posted: May 26, 2000    Key Record Dates
Last Update Posted: February 18, 2016
Last Verified: October 2001

Additional relevant MeSH terms:
Cardiovascular Diseases
Heart Diseases
Lung Diseases
Congenital Abnormalities
Persistent Fetal Circulation Syndrome
Heart Defects, Congenital
Respiratory Tract Diseases
Hypertension, Pulmonary
Infant, Newborn, Diseases
Cardiovascular Abnormalities