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Familial Aggregation and Natural History of Sleep Apnea

This study has been completed.
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Susan Redline, Brigham and Women's Hospital Identifier:
First received: May 25, 2000
Last updated: October 26, 2016
Last verified: October 2016
To quantify the influence of genetic and environmental factors on the development of sleep apnea.

Lung Diseases Sleep Apnea Syndromes

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Susan Redline, Brigham and Women's Hospital:

Primary Outcome Measures:
  • Sleep Apnea

Biospecimen Retention:   Samples With DNA
Samples stored deidentified

Enrollment: 726
Study Start Date: August 1990
Study Completion Date: March 2008
Primary Completion Date: March 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Probands with sleep apnea and family members; neighborhood control families
sleep apnea, or family member or neighbor of proband
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00005299

Sponsors and Collaborators
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Susan Redline Case Western Reserve University
Principal Investigator: Susan Redline, MD Brigham and Women's Hospital
  More Information


Responsible Party: Susan Redline, Professor, Brigham and Women's Hospital Identifier: NCT00005299     History of Changes
Other Study ID Numbers: 2022
R01HL046380-15 ( U.S. NIH Grant/Contract )
Study First Received: May 25, 2000
Last Updated: October 26, 2016

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Lung Diseases
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases processed this record on September 21, 2017