Familial Aggregation and Natural History of Sleep Apnea

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00005299
Recruitment Status : Completed
First Posted : May 26, 2000
Last Update Posted : October 28, 2016
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Susan Redline, Brigham and Women's Hospital

Brief Summary:
To quantify the influence of genetic and environmental factors on the development of sleep apnea.

Condition or disease
Lung Diseases Sleep Apnea Syndromes

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Study Type : Observational
Actual Enrollment : 726 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : August 1990
Actual Primary Completion Date : March 2008
Actual Study Completion Date : March 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sleep Apnea
U.S. FDA Resources

Primary Outcome Measures :
  1. Sleep Apnea

Biospecimen Retention:   Samples With DNA
Samples stored deidentified

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Probands with sleep apnea and family members; neighborhood control families
sleep apnea, or family member or neighbor of proband

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00005299

Sponsors and Collaborators
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Susan Redline Case Western Reserve University
Principal Investigator: Susan Redline, MD Brigham and Women's Hospital


Responsible Party: Susan Redline, Professor, Brigham and Women's Hospital Identifier: NCT00005299     History of Changes
Other Study ID Numbers: 2022
R01HL046380-15 ( U.S. NIH Grant/Contract )
First Posted: May 26, 2000    Key Record Dates
Last Update Posted: October 28, 2016
Last Verified: October 2016

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Lung Diseases
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases