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Epidemiology of Hypertensive Emergency

This study has been completed.
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Columbia University Identifier:
First received: May 25, 2000
Last updated: December 22, 2015
Last verified: December 2015
To test the hypotheses that hypertensive emergency was associated with non-compliance with antihypertensive medication, low level of contact with the medical care system, and alcohol abuse and cigarette smoking. Also, to describe the clinical characteristics of patients hospitalized with hypertensive emergency including morbidity, mortality, and cost, and the extent to which hypertensive emergency occured among previously diagnosed and treated hypertensives.

Cardiovascular Diseases
Heart Diseases

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Correlates of Nonadherence to Hypertension Treatment in an Inner-City Minority Population

Further study details as provided by Columbia University:

Enrollment: 210
Study Start Date: October 1989
Study Completion Date: December 1992
Primary Completion Date: June 1991 (Final data collection date for primary outcome measure)
Detailed Description:


While less frequent than in the era before effective treatment for hypertension, hypertensive emergency remains a relatively common cause of hospital admission in some sub-populations. In 1989, hypertensive emergency accounted for approximately 60 admissions per year to the Medical Service at Presbyterian Hospital, and a somewhat higher proportion of intensive care unit admissions and utilization. The importance of hypertensive emergency may have been underestimated because the International Classification of Diseases discharge codes included only malignant hypertension, a severe form comprising only about half of the admissions for hypertensive emergency. There had been almost no epidemiologic studies of hypertensive emergency since 1969, and very little was known about risk factors.


A matched case-control study design was used. Cases were obtained from admissions to the Medical Service at Presbyterian Hospital. Morbidity and mortality data were obtained by follow-up of the case series.


Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Subjects were enrolled in a case-control study of hypertensive emergency and urgency. Cases were patients with incidents of hypertensive emergency or hypertensive urgency, and controls were hypertensive patients with other acute conditions who were admitted to the hospital or were treated in the emergency room and released.

Inclusion criteria

1. Patients admitted in the emergency room and for the medical and surgical services at the Presbyterian Hospital and Harlem Hospital Center in New York City

  • patients with incidents of hypertensive emergency or hypertensive urgency
  • hypertensive patients with other acute conditions who were admitted to the hospital or were treated in the emergency room and released

Exclusion criteria

  1. Under 21 years of age
  2. Pregnancy
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Please refer to this study by its identifier: NCT00005240

United States, New York
Columbia University
New York, New York, United States, 10032
Sponsors and Collaborators
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Steven Shea, MD Hamilton Southworth Professor of Medicine and Professor of Epide, Dept of Medicine General Medicine
  More Information

Responsible Party: Columbia University Identifier: NCT00005240     History of Changes
Other Study ID Numbers: CUMC ID unknown (1121)
R01HL038260 ( US NIH Grant/Contract Award Number )
Study First Received: May 25, 2000
Last Updated: December 22, 2015

Additional relevant MeSH terms:
Cardiovascular Diseases
Heart Diseases
Vascular Diseases processed this record on May 25, 2017