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Cardiovascular Disease in Black Versus White Physicians

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ClinicalTrials.gov Identifier: NCT00005234
Recruitment Status : Completed
First Posted : May 26, 2000
Last Update Posted : February 18, 2016
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)

Brief Summary:
To examine the natural histories of coronary artery disease and hypertension in cohorts of Black and white men of identical education and occupations.

Condition or disease
Cardiovascular Diseases Coronary Disease Heart Diseases Hypertension

Detailed Description:

BACKGROUND:

Prior studies of Black-white differences in hypertension and coronary disease have compared racial groups from markedly different socioeconomic and educational backgrounds. This study represented one of a few, if any, long term prospective studies of cardiovascular disease in middle-class Blacks and whites of similar education and occupation, in whom both youthful and midlife risk factors were assessed.

DESIGN NARRATIVE:

In this prospective study, the prevalence and incidence of coronary artery disease, hypertension, and other cardiovascular diseases were compared using standardized endpoint criteria. The prevalence of cardiovascular risk factors in midlife were compared between cohorts, and included smoking, diabetes, family history, dietary factors, and lipoprotein cholesterol levels. The youthful predictors of midlife cardiovascular risk factors were determined using baseline data collected by identical protocols in the two cohorts between 1957 and 1965. The youthful risk factors were related to the incidence of disease in midlife in two cohorts to identify differences in significance, independence, and relative importance of risk factors in Blacks versus whites.

The study completion date listed in this record was obtained from the "End Date" entered in the Protocol Registration and Results System (PRS) record.


Study Type : Observational
Study Start Date : September 1988
Actual Study Completion Date : August 1993




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Ages Eligible for Study:   up to 100 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria
No eligibility criteria