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Study of Low Bone Mass in Premenopausal or Perimenopausal Women

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00005101
Recruitment Status : Completed
First Posted : April 7, 2000
Last Update Posted : June 24, 2005
Columbia University
Information provided by:
National Center for Research Resources (NCRR)

Brief Summary:


I. Determine the possible causes of bone loss in premenopausal or perimenopausal women.

Condition or disease

Detailed Description:

PROTOCOL OUTLINE: Patients undergo physical examination and complete history with emphasis on risk factors for osteoporosis and screening for occult secondary causes of osteoporosis through blood serum and 24 hour urine collection.

Patients with more than 6 months since prior bone mineral density measurements or who did not receive measurements at participating center, undergo dual energy x-ray absorptiometry over 30 minutes for bone mineral density measurements.

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Study Type : Observational
Primary Purpose: Screening
Study Start Date : February 1998

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoporosis

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   16 Years to 54 Years   (Child, Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No


--Disease Characteristics--

  • Low bone mass (T score less than -2.0) with no secondary cause on routine exam
  • Premenopausal


  • Perimenopausal

--Prior/Concurrent Therapy--

  • Chemotherapy: No prior or concurrent chemotherapeutic agents
  • Endocrine therapy: No prior or concurrent glucocorticoids or suppressive doses of thyroid hormone
  • Other: No prior or concurrent anticonvulsants

--Patient Characteristics--

  • Hematopoietic: No multiple myeloma
  • Other: No hyperparathyroidism No thyrotoxicosis No anorexia nervosa No Paget's disease of bone No rheumatoid arthritis No Cushing's syndrome No malabsorption syndrome No type I diabetes mellitus

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00005101

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United States, New York
Columbia University College of Physicians and Surgeons
New York, New York, United States, 10032
Sponsors and Collaborators
National Center for Research Resources (NCRR)
Columbia University
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Study Chair: Elizabeth Shane Columbia University
Layout table for additonal information Identifier: NCT00005101    
Other Study ID Numbers: NCRR-M01RR00645-2738
First Posted: April 7, 2000    Key Record Dates
Last Update Posted: June 24, 2005
Last Verified: December 2003
Keywords provided by National Center for Research Resources (NCRR):
disease-related problem/condition
rare disease
Additional relevant MeSH terms:
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Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases