Droxidopa in Treating Patients With Neurogenic Hypotension
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|ClinicalTrials.gov Identifier: NCT00004478|
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : September 18, 2008
Please note that the continuation study can be found at http://clinicaltrials.gov/show/NCT00633880.
RATIONALE: Neurogenic hypotension is a fall in blood pressure that occurs when one moves from a lying down to a standing position or after eating a meal. It causes one to feel dizzy, light headed, and weak. Neurogenic hypotension is caused by a problem in the part of the nervous system that controls such functions as heart rate and blood pressure. Droxidopa, a drug that may increase blood pressure, may be an effective treatment for neurogenic hypotension.
PURPOSE: Clinical trial to study the effectiveness of droxidopa in treating patients who have neurogenic hypotension.
|Condition or disease||Intervention/treatment||Phase|
|Shy-Drager Syndrome Orthostatic Hypotension||Drug: droxidopa||Not Applicable|
Patients receive escalating doses of droxidopa or placebo for 7-14 days. Patients undergo blood pressure measurements hourly in both supine and standing positions.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Study of Droxidopa in Patients With Neurologic Hypotension|
|Study Start Date :||March 1999|
|Actual Primary Completion Date :||March 2006|
|Actual Study Completion Date :||March 2006|
U.S. FDA Resources
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004478
|United States, New York|
|New York University School of Medicine|
|New York, New York, United States, 10016|
|Study Chair:||Horacio Kaufmann, MD||New York University School of Medicine|