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Genetic Linkage Study for Hereditary Pancreatitis

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ClinicalTrials.gov Identifier: NCT00004475
Recruitment Status : Unknown
Verified September 2006 by Office of Rare Diseases (ORD).
Recruitment status was:  Recruiting
First Posted : October 19, 1999
Last Update Posted : September 6, 2006
Sponsor:
Collaborator:
Information provided by:

Study Description
Brief Summary:

OBJECTIVES:

I. Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene.


Condition or disease Intervention/treatment
Pancreatitis Procedure: genetic testing

Detailed Description:

PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients and family members. DNA is extracted from the blood and used for genotypic analysis and linkage analysis.

Patients do not necessarily receive the results of the genetic testing and the results do not influence the type or duration of treatment.


Study Design

Study Type : Observational
Observational Model: Natural History
Study Start Date : December 1998

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pancreatitis
U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
  • Diagnosis of hereditary pancreatitis with confirmation of phenotype by: Onset of pain before age 20 Amylase elevation at least 2 times normal Surgical or postmortem confirmation of pancreatitis Unequivocal evidence of pancreatic exocrine insufficiency in the absence of trauma, alcohol abuse, elevated serum lipids, or other known causes
  • Family member of a patient diagnosed with hereditary pancreatitis
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004475


Locations
United States, Pennsylvania
University of Pittsburgh, Presbyterian University Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15213-2582
Contact: David C. Whitcomb    412-648-9115      
Contact: Beth D. Elinoff    888-748-8362    elinoffb@msx.dept-med.pitt.edu   
Sponsors and Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Pittsburgh
Investigators
Study Chair: David C. Whitcomb University of Pittsburgh
More Information

ClinicalTrials.gov Identifier: NCT00004475     History of Changes
Other Study ID Numbers: 199/14042
UPMC-951061
UPMC-R01DK54709-01
UPMC-R03DK51954
First Posted: October 19, 1999    Key Record Dates
Last Update Posted: September 6, 2006
Last Verified: September 2006

Additional relevant MeSH terms:
Pancreatitis
Pancreatic Diseases
Digestive System Diseases