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Genetic Linkage Study for Hereditary Pancreatitis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2006 by Office of Rare Diseases (ORD).
Recruitment status was:  Recruiting
ClinicalTrials.gov Identifier:
First Posted: October 19, 1999
Last Update Posted: September 6, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
University of Pittsburgh
Information provided by:
Office of Rare Diseases (ORD)


I. Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene.

Condition Intervention
Pancreatitis Procedure: genetic testing

Study Type: Observational
Study Design: Observational Model: Natural History

Resource links provided by NLM:

Further study details as provided by Office of Rare Diseases (ORD):

Study Start Date: December 1998
Detailed Description:

PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients and family members. DNA is extracted from the blood and used for genotypic analysis and linkage analysis.

Patients do not necessarily receive the results of the genetic testing and the results do not influence the type or duration of treatment.


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
  • Diagnosis of hereditary pancreatitis with confirmation of phenotype by: Onset of pain before age 20 Amylase elevation at least 2 times normal Surgical or postmortem confirmation of pancreatitis Unequivocal evidence of pancreatic exocrine insufficiency in the absence of trauma, alcohol abuse, elevated serum lipids, or other known causes
  • Family member of a patient diagnosed with hereditary pancreatitis
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004475

United States, Pennsylvania
University of Pittsburgh, Presbyterian University Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15213-2582
Contact: David C. Whitcomb    412-648-9115      
Contact: Beth D. Elinoff    888-748-8362    elinoffb@msx.dept-med.pitt.edu   
Sponsors and Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Pittsburgh
Study Chair: David C. Whitcomb University of Pittsburgh
  More Information

ClinicalTrials.gov Identifier: NCT00004475     History of Changes
Other Study ID Numbers: 199/14042
First Submitted: October 18, 1999
First Posted: October 19, 1999
Last Update Posted: September 6, 2006
Last Verified: September 2006

Additional relevant MeSH terms:
Pancreatic Diseases
Digestive System Diseases