Longitudinal and Biological Study of Childhood Disintegrative Disorder
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|ClinicalTrials.gov Identifier: NCT00004458|
Recruitment Status : Terminated
First Posted : October 19, 1999
Last Update Posted : June 24, 2005
I. Compare the developmental course (language acquisition, diagnostic stability, predictors of outcome, and restricted interests and behaviors) of childhood disintegrative disorder versus autism and non-autistic developmental delays.
II. Collect data on molecular genetics of proband and family members.
|Condition or disease|
|Pervasive Child Development Disorders Autism|
Patients are evaluated with the following questionnaires at ages 2-3 years and again at ages 5-9: The Autism Diagnostic Interview (ADI); The Autism Diagnostic Observation Schedule (ADOS); Assessment of cognitive functioning; Expressive and receptive language; Adaptive functioning; Measures of burden and functional assessment; The Aberrant Behavior Checklist; The Connors Rating Scale - Parent and Teacher version; and Autism Behavior Checklist
An MRI and EEG are performed, and blood samples are collected from patients and family members for molecular genetic studies.
|Study Type :||Observational|
|Estimated Enrollment :||220 participants|
|Study Start Date :||May 1997|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004458
|United States, Connecticut|
|Yale Child Study Center|
|New Haven, Connecticut, United States, 06520|
|United States, Illinois|
|University of Chicago Cancer Research Center|
|Chicago, Illinois, United States, 60637|
|Study Chair:||Fred Volkmar||Yale University|