Study of Gammalinolenic Acid for Juvenile Rheumatoid Arthritis
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|ClinicalTrials.gov Identifier: NCT00004420|
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : March 25, 2015
I. Determine the efficacy and safety of gammalinolenic acid in the treatment of childhood arthritis.
|Condition or disease||Intervention/treatment|
|Juvenile Rheumatoid Arthritis||Drug: gamma-Linolenic acid|
PROTOCOL OUTLINE: This is a randomized, double blind, placebo controlled, cross over study of 12 months duration. Patients are stratified by type of juvenile rheumatoid arthritis (systemic onset vs pauciarticular disease vs polyarticular disease).
Patients are randomized to receive either gammalinolenic acid (GLA) or placebo (safflower seed oil) orally. Parents are asked to maintain the child's usual diet over the course of study.
Patients are followed at 3, 6, 9, and 12 months during study and at 6 months thereafter.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Intervention Model:||Crossover Assignment|
|Study Start Date :||September 1994|
|Estimated Study Completion Date :||August 1999|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004420
|Study Chair:||Robert B. Zurier||University of Massachusetts, Worcester|