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Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction

This study has been completed.
University of Pittsburgh
Information provided by:
Office of Rare Diseases (ORD) Identifier:
First received: October 18, 1999
Last updated: June 23, 2005
Last verified: June 2000


I. Evaluate whether vestibular rehabilitation training is of value in reducing anxiety symptoms in patients with panic disorder with or without agoraphobia who have vestibular dysfunction as identified by clinical vestibular tests.

Condition Intervention
Vestibular Diseases Agoraphobia Panic Disorder Procedure: Physical therapy

Study Type: Interventional
Study Design: Primary Purpose: Educational/Counseling/Training

Resource links provided by NLM:

Further study details as provided by Office of Rare Diseases (ORD):

Estimated Enrollment: 20
Study Start Date: August 1995
Estimated Study Completion Date: May 2000
Detailed Description:

PROTOCOL OUTLINE: During the first 4 weeks of study, patients meet with a clinical nurse specialist once a week for approximately 1 hour. During this time, the nature of the anxiety disorder is explained and exposure to previously feared situations is encouraged.

Only patients who remain symptomatic at a stable level following self-exposure will proceed with rehabilitation training.

Patients meet with a physical therapist once a week for 4 weeks to further evaluate the extent of problems associated with balance. Then, patients undergo weekly 1 hour exercises for 8 weeks with the physical therapist, focusing on sensation, head and eye coordination, movement with eyes opened and closed, and gait.

Concurrently, patients meet with the clinical nurse specialist every 4 weeks during and after physical therapy to evaluate the effects of vestibular treatment on anxiety symptoms.

Training is continued if patient is symptomatic; otherwise, patient is discharged from study.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
  • Diagnosed panic disorder with or without agoraphobia
  • Vestibular dysfunction, as defined by abnormalities in the caloric and/or rotational tests
  • Continued symptomatology after general instructions of the importance of exposure to feared situations
  • Absence of acute symptoms of anxiety or depression assessed to need immediate clinical care
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Please refer to this study by its identifier: NCT00004366

Sponsors and Collaborators
National Center for Research Resources (NCRR)
University of Pittsburgh
Study Chair: Rolf G. Jacob University of Pittsburgh
  More Information Identifier: NCT00004366     History of Changes
Other Study ID Numbers: 199/11944
Study First Received: October 18, 1999
Last Updated: June 23, 2005

Keywords provided by Office of Rare Diseases (ORD):
anxiety disorder
disease-related problem/condition
neurologic and psychiatric disorders
panic disorder
rare disease
vestibular diseases

Additional relevant MeSH terms:
Panic Disorder
Vestibular Diseases
Pathologic Processes
Anxiety Disorders
Mental Disorders
Labyrinth Diseases
Ear Diseases
Otorhinolaryngologic Diseases processed this record on August 16, 2017