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Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00004366
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : June 24, 2005
University of Pittsburgh
Information provided by:
Office of Rare Diseases (ORD)

Brief Summary:


I. Evaluate whether vestibular rehabilitation training is of value in reducing anxiety symptoms in patients with panic disorder with or without agoraphobia who have vestibular dysfunction as identified by clinical vestibular tests.

Condition or disease Intervention/treatment Phase
Vestibular Diseases Agoraphobia Panic Disorder Procedure: Physical therapy Not Applicable

Detailed Description:

PROTOCOL OUTLINE: During the first 4 weeks of study, patients meet with a clinical nurse specialist once a week for approximately 1 hour. During this time, the nature of the anxiety disorder is explained and exposure to previously feared situations is encouraged.

Only patients who remain symptomatic at a stable level following self-exposure will proceed with rehabilitation training.

Patients meet with a physical therapist once a week for 4 weeks to further evaluate the extent of problems associated with balance. Then, patients undergo weekly 1 hour exercises for 8 weeks with the physical therapist, focusing on sensation, head and eye coordination, movement with eyes opened and closed, and gait.

Concurrently, patients meet with the clinical nurse specialist every 4 weeks during and after physical therapy to evaluate the effects of vestibular treatment on anxiety symptoms.

Training is continued if patient is symptomatic; otherwise, patient is discharged from study.

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Study Type : Interventional  (Clinical Trial)
Enrollment : 20 participants
Primary Purpose: Educational/Counseling/Training
Study Start Date : August 1995
Study Completion Date : May 2000

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Panic Disorder

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
  • Diagnosed panic disorder with or without agoraphobia
  • Vestibular dysfunction, as defined by abnormalities in the caloric and/or rotational tests
  • Continued symptomatology after general instructions of the importance of exposure to feared situations
  • Absence of acute symptoms of anxiety or depression assessed to need immediate clinical care

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00004366

Sponsors and Collaborators
National Center for Research Resources (NCRR)
University of Pittsburgh
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Study Chair: Rolf G. Jacob University of Pittsburgh
Layout table for additonal information Identifier: NCT00004366    
Other Study ID Numbers: 199/11944
First Posted: October 19, 1999    Key Record Dates
Last Update Posted: June 24, 2005
Last Verified: June 2000
Keywords provided by Office of Rare Diseases (ORD):
anxiety disorder
disease-related problem/condition
neurologic and psychiatric disorders
panic disorder
rare disease
vestibular diseases
Additional relevant MeSH terms:
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Vestibular Diseases
Panic Disorder
Pathologic Processes
Anxiety Disorders
Mental Disorders
Labyrinth Diseases
Ear Diseases
Otorhinolaryngologic Diseases