Study of Pituitary Size and Function in Familial Dwarfism of Sindh
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00004365|
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : June 24, 2005
OBJECTIVES: I. Assess pituitary size and anatomic configuration by magnetic resonance imaging (MRI) in 4 affected dwarfs in the province of Sindh, Pakistan.
II. Evaluate ultradian growth hormone (GH) secretory patterns in 4 affected dwarfs.
|Condition or disease|
|Growth Hormone Deficiency|
PROTOCOL OUTLINE: Pituitary size and anatomy and growth hormone response are evaluated.
All patients undergo MRI of the pituitary fossa on day 1. On day 2, homozygous patients receive a slow infusion of normal saline with blood sampling every 10 minutes.
|Study Type :||Observational|
|Estimated Enrollment :||4 participants|
|Study Start Date :||September 1995|
|Estimated Study Completion Date :||February 2000|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004365
|Study Chair:||Gerhard Baumann||Northwestern University|