Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia
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|ClinicalTrials.gov Identifier: NCT00004353|
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : July 10, 2008
OBJECTIVES: I. Study the metabolism of pyruvate and related problems in patients with lactic acidemia.
II. Define the nature of the metabolic defect.
|Condition or disease|
|Mitochondrial Myopathy MELAS Syndrome Lactic Acidosis|
PROTOCOL OUTLINE: Patients fast for 6 hours. Glucagon IM is administered after the 6 hour fast. Glucose level is measured at 0, 15, 30, 45, 60, and 90 minutes.
In children of sufficient size, alanine and lactic acid should also be measured at each or most of these time points.
Fasting continues for at least 18 hours. Glucagon IM is administered again at end of fast. Glucose level is measured at time 0, 15, 30, 45, 60, and 90 minutes.
|Study Type :||Observational|
|Estimated Enrollment :||35 participants|
|Study Start Date :||December 1978|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004353
|United States, California|
|University of California San Diego Medical Center|
|San Diego, California, United States, 92103-8757|
|Study Chair:||Richard H. Haas||University of California, San Diego|