Purification of Testis-Stimulating Factor in Precocious Puberty
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|ClinicalTrials.gov Identifier: NCT00004344|
Recruitment Status : Completed
First Posted : October 19, 1999
Last Update Posted : June 24, 2005
Purify and characterize a testis-stimulating factor in the blood of adult volunteers who had precocious puberty as boys.
|Condition or disease||Intervention/treatment|
|Precocious Puberty||Drug: leuprolide Drug: testosterone|
PROTOCOL OUTLINE: Subjects are treated for 2 months with depot injections of leuprolide acetate every 4 weeks and testosterone replacement every 2 weeks. Hormone levels are tested every other week.
If luteinizing hormone and follicular-stimulating hormone levels are at or below detection on day 56, blood is drawn for a testis-stimulating factor bioassay and subsequent factor purification and characterization.
Volunteers are asked to repeat this 2-month procedure no more than 2 times every 12 months.
|Study Type :||Observational|
|Estimated Enrollment :||4 participants|
|Study Start Date :||January 1997|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00004344
|Study Chair:||Barry Albertson||Oregon Health and Science University|