International Registry for Severe Chronic Neutropenia
Recruitment status was: Recruiting
OBJECTIVES: I. Document the clinical course of severe chronic neutropenia (SCN).
II. Monitor and assess long term safety of primary treatment in SCN patients in the United States, Canada, Europe, and Australia.
III. Study the incidence and outcome of adverse events such as osteoporosis, splenomegaly, cytogenetic abnormalities, myelodysplastic syndrome, and leukemia.
IV. Evaluate growth and development and hematologic parameters. V. Monitor for clinically significant changes in primary treatment response over time.
VI. Establish a physician network to increase the understanding of SCN. VII. Establish a demographic database to allow for future research.
|Study Design:||Observational Model: Natural History|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004342
|United States, Michigan|
|Ann Arbor, Michigan, United States, 48109-0266|
|United States, New Jersey|
|St. Barnabas Medical Center|
|Livingston, New Jersey, United States, 07039|
|United States, Washington|
|University of Washington School of Medicine|
|Seattle, Washington, United States, 98195|
|Central Highlands Oncology Program|
|Ballarat, Victoria, Australia, 3350|
|Winnipeg, Manitoba, Canada, R3E 0V9|
|Hospital for Sick Children|
|Toronto, Ontario, Canada, M5G 1X8|
|Medizinische Hochschule Hannover|
|Hannover, Germany, D-30625|
|Istituto Giannina Gaslini|
|Genova, Italy, 16148|
|St. James's Hospital|
|Leeds, England, United Kingdom, LS9 7TF|
|Study Chair:||David Chandler Dale||University of Washington|