Cryosurgery in Treating Patients With Liver Cancer or Liver Metastases
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|ClinicalTrials.gov Identifier: NCT00002655|
Recruitment Status : Completed
First Posted : August 11, 2004
Last Update Posted : July 22, 2013
RATIONALE: Cryosurgery kills cancer cells by freezing them during surgery.
PURPOSE: Phase I/II trial to study the effectiveness of cryosurgery in treating patients with unresectable primary liver cancer or liver metastases.
|Condition or disease||Intervention/treatment||Phase|
|Liver Cancer Metastatic Cancer||Procedure: cryosurgery||Phase 2|
OBJECTIVES: I. Assess the safety and efficacy of liquid nitrogen necrosis of liver lesions using a commercially available intraoperative cryosurgical system, with placement of the cryoprobe and subsequent monitoring by high-resolution ultrasound. II. Use this technique on selected patients with surgically unresectable metastatic or primary liver cancer whose disease appears confined to the liver and who are potentially curable if all tumor in the liver can be destroyed. III. Quantitate the quality and duration of survival, identify recurrence of hepatic malignant disease, and identify any morbidity from the procedure.
OUTLINE: Cryosurgery. Liquid nitrogen freezing of tumor using a cryoprobe placed and maintained under ultrasound guidance.
PROJECTED ACCRUAL: 50 patients will be treated.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Cryosurgical Destruction of Surgically Incurable Liver Tumors|
|Study Start Date :||March 1995|
|Actual Primary Completion Date :||September 1999|
|Actual Study Completion Date :||September 1999|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00002655
|United States, Colorado|
|University of Colorado Cancer Center|
|Denver, Colorado, United States, 80262|
|Study Chair:||Greg V. Stiegmann, MD||University of Colorado, Denver|