Safety and Effects of Giving a New HIV Vaccine (GENEVAX-HIV) to HIV-Negative Volunteers
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
The purpose of this study is to see if it is safe to give GENEVAX-HIV, a new HIV vaccine, to HIV-negative volunteers. This study will also look at how this vaccine affects the immune system of these volunteers.
Condition or disease
HIV InfectionsHIV Seronegativity
Biological: APL 400-003
In this open-label study, volunteers are given an intramuscular injection of GENEVAX-HIV vaccine using the Biojector 2000. Safety measures and immune response are assessed accordingly.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years to 60 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
You may be eligible for this study if you:
Are 18 - 60 years old.
Are HIV-negative and in good health.
Are able to understand how infections such as HIV are spread.
Agree to use effective methods of birth control during the study.
You will not be eligible for this study if you:
Have hepatitis B or C.
Have any condition that may prevent you from completing the study.
Are allergic to bupivacaine, vaccines, or certain local anesthetics.
Have taken certain medications or have received certain therapies that may affect your immune system.
Have an immune system disorder or have received therapy for an immune system disorder.
Have been exposed to HIV within 6 months prior to study entry.
Have received an experimental HIV vaccine or any other experimental treatment within 30 days prior to study entry.
Have received blood transfusions within 6 months prior to study entry.
Abuse alcohol or drugs or have an uncontrolled psychiatric disorder.