Sample Collections From the Airways of Asthmatic Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00001888|
Recruitment Status : Recruiting
First Posted : November 4, 1999
Last Update Posted : November 3, 2021
Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to the airway and gently suctioning it back into the bronchoscope (bronchoalveolar lavage) collects cells.
In this study, researchers plan to perform these tests on patients with asthma and normal volunteers. This research may help to improve the understanding of the processes involved in airway inflammation and asthma.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||2000 participants|
|Official Title:||Asthma Sample Collection Protocol|
|Actual Study Start Date :||June 2, 1999|
- Assess the expression, regulation, and function of proteins regulating the release of soluble receptors and mediators from asthmatic inflammatory and structural cell populations [ Time Frame: Ongoing ]These studies will increase understanding of the pathogenic mechanisms underlying asthmatic airway inflammation and may identify novel therapeutic targets.
- Assess the role of apolipoprotein and lipid pathways in asthmatic and non-asthmatic subjects [ Time Frame: Ongoing ]Assess the role of apolipoprotein and lipid pathways in asthmatic and non-asthmatic subjects
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001888
|Contact: Joni Y Mills, C.R.N.P.||(301) firstname.lastname@example.org|
|Contact: Stewart J Levine, M.D.||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
|Principal Investigator:||Stewart J Levine, M.D.||National Heart, Lung, and Blood Institute (NHLBI)|