Evaluation for NCI Surgery Branch Clinical Research Protocols
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|ClinicalTrials.gov Identifier: NCT00001823|
Recruitment Status : Recruiting
First Posted : November 4, 1999
Last Update Posted : June 30, 2020
The National Cancer Institute Surgery Branch (NCI-SB) has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the laboratory in large numbers, and then giving the cells back to the patient.
This study will allow patients to under screening and evaluation for participation in NC-SB Protocols.
Patients 18 years or older must meet the minimum eligibility criteria for an NCI-SB treatment protocol.
Patients will undergo testing and evaluations as required by the appropriate NCI-SB treatment protocol.
|Condition or disease|
|Synovial Cell Cancer Melanoma Colorectal Cancer Lung Cancer Bladder Cancer|
Potential research candidates undergo thorough screening including laboratory tests, scans, x-rays, and review of pathology slides to determine initial eligibility for National Cancer Institute Surgery Branch (NCI-SB) research protocols.
Permit evaluation of patients referred to the NCI-SB in order to identify individuals who will be suitable candidates for NCI-SB clinical research protocols.
To assess frequency of HLA type, gene specific mutations or expression of neo antigens in malignant tumors across the population of cancer patients undergoing screening for NCI-SB protocols.
Collect results of screening tests for use on subsequent research protocol as baseline (e.g., pretreatment) values.
Age >= 18 years and <= 70 years.
Patient suspected of having, or with biopsy proven, malignant disease.
Patient is able to understand and willing to sign a written informed consent document.
Patient is being evaluated for treatment on an NCI-SB protocols..
Patients enrolled on this protocol will be evaluated by NCI-SB physicians to determine the individual's suitability for participation in a clinical research protocol. An accrual ceiling of 6000 patients has been set to meet the screening needs of the NCI-SB.
|Study Type :||Observational|
|Estimated Enrollment :||6000 participants|
|Official Title:||Evaluation for NCI Surgery Branch Clinical Research Protocols|
|Actual Study Start Date :||July 11, 1999|
A/Surgery Branch Protocol Candidates
Patients suspected of having, or with biopsy proven, malignant disease being evaluated for or treated on NCI Surgery Branch protocols
- Number of individuals suitable for NCI Surgery Branch clinical research protocols [ Time Frame: 25 Years ]Total number of patients who enroll on NCI Surgery Branch clinical research protocols
- Frequency of HLA type, gene specific mutations, or expression of neoantigens in malignant tumors [ Time Frame: 25 years ]Frequency of HLA type, gene specific mutations, or expression of neoantigens in tissue and blood samples
- Results of screening tests [ Time Frame: 25 years ]Results of screening tests for use on subsequent research protocol as baseline (e.g., pretreatment) values
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001823
|Contact: For more information NCI/Surgery Branch Recruitment Center||(866) 820-4505||IRC@nih.gov|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact NCI/Surgery Branch Recruitment Center 866-820-4505 firstname.lastname@example.org|
|Principal Investigator:||Steven A Rosenberg, M.D.||National Cancer Institute (NCI)|