Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy
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|ClinicalTrials.gov Identifier: NCT00001666|
Recruitment Status : Completed
First Posted : November 4, 1999
Last Update Posted : March 4, 2008
Transcranial Magnetic Stimulation (TMS) is a non-invasive technique that can be used to stimulate brain activity and gather information about brain function. It is very useful when studying the areas of the brain related to motor activity (motor cortex, corticospinal tract, and corpus callosum).
Epilepsy is a condition associated with seizures as a result of an over excitable cerebral cortex. Despite the introduction of several new antiepileptic medications, less than half of the patients diagnosed with partial epilepsy are well controlled. However, studies have shown that non-invasive stimulation of the brain can decrease the excitability of the cerebral cortex.
Researchers are interested in the potential therapeutic effects of TMS on patients with epilepsy that have responded poorly to standard medication. This study will use TMS to decrease the excitability of the areas of the brain responsible for seizures.
|Condition or disease||Intervention/treatment|
|Partial Epilepsy Seizures||Device: Cadwell High-Speed Magnetoelectric Stimulator Device: Magpro High-Speed Magnetoelectric Stimulator|
|Study Type :||Observational|
|Estimated Enrollment :||32 participants|
|Official Title:||Drug Refractory Partial Epilepsy, A Therapeutic Trial With Transcranial Magnetic Stimulation|
|Study Start Date :||March 1997|
|Estimated Study Completion Date :||June 2002|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001666
|United States, Maryland|
|National Institute of Neurological Disorders and Stroke (NINDS)|
|Bethesda, Maryland, United States, 20892|