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Diagnosis and History Study of Patients With Different Neurological Conditions

This study is currently recruiting participants.
See Contacts and Locations
Verified May 30, 2017 by National Institutes of Health Clinical Center (CC) ( National Institute of Neurological Disorders and Stroke (NINDS) )
Sponsor:
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Institute of Neurological Disorders and Stroke (NINDS) )
ClinicalTrials.gov Identifier:
NCT00001367
First received: November 3, 1999
Last updated: June 30, 2017
Last verified: May 30, 2017
  Purpose

The goal of this study is to diagnose and follow patients with disorders of movement control. Patients participating in this study will undergo routine laboratory tests and examinations in order to monitor their condition.

Doctors at the NIH will work in cooperation with each patient's primary care physician. There will be no use of investigational treatments in this study.<TAB>


Condition
Nervous System Disease

Study Type: Observational
Official Title: Diagnosis and Natural History Protocol for Patients With Different Neurological Conditions

Resource links provided by NLM:


Further study details as provided by National Institutes of Health Clinical Center (CC) ( National Institute of Neurological Disorders and Stroke (NINDS) ):

Estimated Enrollment: 4000
Study Start Date: August 20, 1993
Detailed Description:

Objective:

This protocol is a screening protocol, which allows for evaluation of patients and families where neurological conditions are present for enrollment into other studies. It is also a teaching and training instrument for the MNB fellows, allowing them to gain expertise in the evaluation and treatment of patients.

Study population:

Subjects with neurological disorders or a family member with a neurological disorder may be eligible to undergo a clinical evaluation. Subjects must be 2 years old or older. National Institutes of Health (NIH) employees (other than those employed by HMCS in NINDS) may participate.

Design:

The goal is to screen patients with neurological conditions and family members of patients with neurological conditions for enrollment in additional research protocols. No investigational treatments will be administered on this protocol and the NIH physicians will be playing a consultative role to the patient s primary physician.

Outcome measures:

This is a natural history screening protocol to evaluate patients with neurological disorders and their family members. Therefore, there is no outcome measure.

  Eligibility

Ages Eligible for Study:   2 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
  • INCLUSION CRITERIA:

Patients with neurological disorders and subjects with a family history of neurological conditions.

EXCLUSION CRITERIA:

  • Patients <2 years old.
  • Employees of HMCS in NINDS.

EXCLUSION CRITERIA FOR MRI:

We will follow the Clinical Radiology/NMR Center guidelines for MR safety. Some of the exclusions are:

  • Have non-MRI compatible metal in the body, such as a cardiac pacemaker, brain stimulator, shrapnel, surgical metal, clips in the brain or on blood vessels, cochlear implants, artificial heart valves or metal fragments in the eye as these make having an MRI unsafe.
  • Have metallic dental fillings which are likely to cause MRI artifacts
  • Unable to lie flat on the back for the expected length of the experiment, up to 30 mins.
  • Uncomfortable being in a small space for the expected length of the experiment, up to 30 mins.
  • Pregnancy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001367

Contacts
Contact: Elaine P Considine, R.N. (301) 435-8518 considinee@ninds.nih.gov
Contact: Mark Hallett, M.D. (301) 496-9526 hallettm@ninds.nih.gov

Locations
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)    800-411-1222 ext TTY8664111010    prpl@mail.cc.nih.gov   
Sponsors and Collaborators
National Institute of Neurological Disorders and Stroke (NINDS)
Investigators
Principal Investigator: Mark Hallett, M.D. National Institute of Neurological Disorders and Stroke (NINDS)
  More Information

Additional Information:
Responsible Party: National Institute of Neurological Disorders and Stroke (NINDS)
ClinicalTrials.gov Identifier: NCT00001367     History of Changes
Other Study ID Numbers: 930202
93-N-0202
Study First Received: November 3, 1999
Last Updated: June 30, 2017

Keywords provided by National Institutes of Health Clinical Center (CC) ( National Institute of Neurological Disorders and Stroke (NINDS) ):
Human
Movement
Non-Investigational to Diagnostic Puzzle
Parkinson's
Dystonia
Cerebellar
Puzzles
Neurological Disorders
Movement Disorders

Additional relevant MeSH terms:
Nervous System Diseases

ClinicalTrials.gov processed this record on August 18, 2017