Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers
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|ClinicalTrials.gov Identifier: NCT00001284|
Recruitment Status : Completed
First Posted : November 4, 1999
Last Update Posted : March 21, 2018
The purpose of this study is to use brain imaging technology to compare differences in brain structure, chemistry, and functioning in individuals with brain and mental disorders compared to healthy volunteers.
Schizophrenia is a brain disorder that results from subtle changes and abnormalities in neurons. These deficits likely occur in localized regions of the brain and may result in widespread, devastating consequences. The neuronal abnormalities are inherited through a complex combination of genetic and environmental factors. Brain imaging technologies can be used to better characterize brain changes in individuals with schizophrenia. This study will use magnetic resonance imaging (MRI) scans to identify predictable, quantifiable abnormalities in neurophysiology, neurochemistry and neuroanatomy that characterize schizophrenia and other neurological and neuropsychiatric disorders.
|Condition or disease|
|Genotype Allelic Frequencies of Genetic Markers Brain Mapping Brain Disease fMRI|
|Study Type :||Observational|
|Actual Enrollment :||2802 participants|
|Official Title:||Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers With 1.5 Tesla MRI|
|Study Start Date :||May 10, 1991|
- Brain Activation [ Time Frame: Per MRI Scan ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001284
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Principal Investigator:||Karen F Berman, M.D.||National Institute of Mental Health (NIMH)|