Studies of Elevated Parathyroid Activity
Patients whose parathyroid activity is elevated above normal are referred to as having hyperparathyroidism. This study will help researchers better understand the causes of hyperthyroidism and to evaluate and improve methods for diagnosis and treatment.
In this study, patients diagnosed with or suspected of having hyperparathyroidism will be selected to participate. In addition, patients with related conditions such as parathyroid tumors, will also be selected.
Subjects will be asked to provide blood and urine for testing to confirm their condition. They will then be surgically treated by removal of the parathyroid gland(s) (parathyroidectomy).
Subjects with parathyroid tumors will undergo several diagnostic tests to determine the exact location of the tumor as well as the tumor's activity. The tests may include; ultrasounds, nuclear scanning, CT scans, MRI, and specialized blood testing.
Sometimes parathyroidectomy leads to hypoparathyroidism. Options for treating the patients after the surgical procedure will also be addressed. Calcium and Vitamin D supplements are typically the mainstay of post parathyroidectomy therapy. Other potential treatments include transplanting the parathyroid gland(s) to other areas of the body.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Studies of Hyperparathyroidism and Related Disorders|
- Evaluate natural history of hyperparathyroidism [ Time Frame: On-going ] [ Designated as safety issue: No ]
|Study Start Date:||March 1991|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00001277
|Contact: Stephen J Marx, M.D.||(301) firstname.lastname@example.org|
|Contact: William F Simonds, M.D.||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
|Principal Investigator:||William F Simonds, M.D.||National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|