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Evaluation of the Causes and Disease Processes of Chronic Lung Disease

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2014 by National Institutes of Health Clinical Center (CC)
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) ) Identifier:
First received: November 3, 1999
Last updated: November 11, 2014
Last verified: March 2014

Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood. This includes abnormalities in the airways, lungs, blood vessels in and around the lungs, and the tissue covering the lungs (pleura).

The purpose of this research study is to evaluate patients referred to the Pulmonary-Critical Care Medicine Branch (P-CCMB) of the National Heart, Lung, and Blood Institute (NHLBI) in order to;

  1. < TAB> Develop a better understanding of the causes and disease processes involved in disorders of the lungs
  2. < TAB> Identify patients eligible to participate in other P-CCMB research studies

Lung Disease

Study Type: Observational
Official Title: Comprehensive Evaluation of the Etiology and Pathogenesis of Chronic Lung Disease (Screening Protocol)

Resource links provided by NLM:

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment: 99999999
Study Start Date: March 1982
Detailed Description:

The chronic lung diseases are those disorders associated with functional and/or structural derangement to the alveolar structures, airways, pulmonary blood vessels, pleura and/or mediastinum. The purpose of this project is to permit the comprehensive evaluation of patients referred to the Cardiovascular and Pulmonary Branch of the National Heart, Lung and Blood Institute (NHLBI) in order to: (1) develop an understanding of the etiology and pathogenesis of these disorders; and (2) identify individuals who will be suitable candidates for other NHLBI protocols.


Ages Eligible for Study:   9 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Symptoms consistent with pulmonary disease.

May have family history of lung disease.

Patients with diseases of organs with known association with lung disease.

Ranging in age from 9 to 90 years old.


Persons with no clinical evidence of lung disease.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00001183

Contact: Mary Haughey, R.N. (301) 496-3632
Contact: Joel Moss, M.D. (301) 496-1597

United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)    800-411-1222 ext TTY8664111010   
Sponsors and Collaborators
Principal Investigator: Joel Moss, M.D. National Heart, Lung, and Blood Institute (NHLBI)
  More Information

Additional Information:
Responsible Party: National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) ) Identifier: NCT00001183     History of Changes
Other Study ID Numbers: 820032, 82-H-0032
Study First Received: November 3, 1999
Last Updated: November 11, 2014
Health Authority: United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Computed Tomography
Fiberoptic Bronchoscopy
Pulmonary Function Testing
Cardiopulmonary Exercise Testing
Allergen Skin Testing
Chronic Lung Disease

Additional relevant MeSH terms:
Lung Diseases
Respiratory Tract Diseases processed this record on March 03, 2015