Evaluation of Patients With Thyroid Disorders

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2015 by National Institutes of Health Clinical Center (CC)
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) )
ClinicalTrials.gov Identifier:
First received: November 3, 1999
Last updated: June 3, 2015
Last verified: May 2015

Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, Graves' Dermopathy, and thyroid-stimulating hormone (TSH) secreting pituitary adenomas.

The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of thyroid function disorders. Many of the tests performed are in the context of standard medical care that is offered to all patients with thyroid function disorders. In addition, blood and tissue samples may be taken for research and genetic studies....


Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Evaluation of Patients With Thyroid Function Disorders

Resource links provided by NLM:

Further study details as provided by National Institutes of Health Clinical Center (CC):

Primary Outcome Measures:
  • Evaluation of Thyroid disorders.

Estimated Enrollment: 99999999
Study Start Date: January 1977
Detailed Description:

Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied and

treated in this protocol. A limited number of patients with a personal history of signs, symptoms or laboratory studies consistent with thyroid dysfunction or a strong family history of thyroid abnormalities are also enrolled. Patients undergo routine history and physical examination, standard endocrine blood and urine tests, a standard TRH test, thyroid nuclear medicine scan, thyroidal radioiodine (RAI) or technetium (99mTc) uptake measurements, as well as X-ray, computed tomography (CT) or magnetic resonance imaging (MRI) studies or other standard diagnostic procedures, as clinically indicated. Patients will be screened for entry into other research studies.


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Patients of any age with known or suspected thyroid abnormalities may be included in this study. These disorders can be broadly defined as hyper- or hypothyroid states and laboratory abnormalities.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001159

Contact: Craig S Cochran, R.N. (301) 402-1880 craigc@bdg10.niddk.nih.gov
Contact: Monica C Skarulis, M.D. (301) 496-6087 monicas@intra.niddk.nih.gov

United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)    800-411-1222 ext TTY8664111010    prpl@mail.cc.nih.gov   
Sponsors and Collaborators
Principal Investigator: Monica C Skarulis, M.D. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  More Information

Additional Information:
Responsible Party: National Institutes of Health Clinical Center (CC) ( National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) )
ClinicalTrials.gov Identifier: NCT00001159     History of Changes
Other Study ID Numbers: 770002, 77-DK-0002
Study First Received: November 3, 1999
Last Updated: June 3, 2015
Health Authority: United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Thyroid-Stimulating Hormone Secreting Pituitary Adenomas

Additional relevant MeSH terms:
Endocrine System Diseases
Thyroid Diseases

ClinicalTrials.gov processed this record on September 01, 2015