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Mode Selection Trial in Sinus Node Dysfunction (MOST)

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ClinicalTrials.gov Identifier: NCT00000561
Recruitment Status : Completed
First Posted : October 28, 1999
Last Update Posted : February 23, 2016
Sponsor:
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:
Mt. Sinai Medical Center, Miami

Brief Summary:
To determine if dual chamber rate-modulated pacing (DDDR) in patients with sick sinus syndrome is superior to single chamber pacing (VVIR) with respect to subsequent frequency of adverse clinical events such as stroke, quality of life and function, and cost effectiveness.

Condition or disease Intervention/treatment Phase
Arrhythmia Cardiovascular Diseases Heart Diseases Sick Sinus Syndrome Vascular Diseases Cerebrovascular Accident Device: pacemaker, artificial Phase 3

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Primary Purpose: Treatment
Study Start Date : June 1995
Study Completion Date : May 2002

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Men and women with sick sinus syndrome.

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000561


Sponsors and Collaborators
Mt. Sinai Medical Center, Miami
National Heart, Lung, and Blood Institute (NHLBI)
Investigators
OverallOfficial: Gervasio Lamas Icahn School of Medicine at Mount Sinai
OverallOfficial: Kerry Lee Duke University

Publications:

ClinicalTrials.gov Identifier: NCT00000561     History of Changes
Other Study ID Numbers: 105
U01HL049804 ( U.S. NIH Grant/Contract )
First Posted: October 28, 1999    Key Record Dates
Last Update Posted: February 23, 2016
Last Verified: May 2005

Additional relevant MeSH terms:
Sick Sinus Syndrome
Cardiovascular Diseases
Heart Diseases
Vascular Diseases
Stroke
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Arrhythmia, Sinus
Arrhythmias, Cardiac
Heart Block
Pathologic Processes