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Bypass Angioplasty Revascularization Investigation (BARI)

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI) Identifier:
First received: October 27, 1999
Last updated: May 12, 2016
Last verified: March 2005
To assess the relative long-term safety and efficacy of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass graft (CABG) surgery in patients with multivessel disease and severe angina or ischemia who required revascularization and had coronary anatomy suitable for either procedure.

Condition Intervention Phase
Angina Pectoris Cardiovascular Diseases Coronary Disease Diabetes Mellitus Heart Diseases Myocardial Ischemia Procedure: angioplasty, transluminal, percutaneous coronary Procedure: coronary artery bypass Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: April 1987
Estimated Study Completion Date: November 2004
  Show Detailed Description


Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Multivessel coronary artery disease requiring revascularization and suitable for either PTCA or CABG.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00000462

Sponsors and Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
OverallOfficial: Katherine Detre University of Pittsburgh
  More Information

BARI Investigators: Protocol for the Bypass Angioplasty Revascularization Investigation. Supplement to Circulation, 84:6, 1991.
Rosen AD: A SAS Interface to System 1032: Writing a user-maintainable interface to data management systems. Proc of Seventeenth Annual SAS Users Group International Conference, Cary, NC, SAS Institute Inc. pp 313, 1992.
Alderman E, Stadius M: The angiographic definitions of the Bypass Angioplasty Revascularization Investigation. Current Science, 3:1189-1207, 1992.
Letters to the Editor: Bypass Angioplasty Revascularization Investigation. N Engl J Med, 336:136-138, 1997.
Frye RL, King SB III, Sopko G, et al (Eds): A Symposium: Multivessel PTCA Versus CABG: Baseline Data from the Bypass Angioplasty Revascularization Investigation (BARI) and the Emory Angioplasty Surgery Trial (EAST). Am J Cardiol, 75: 1C-59C, 1995. Identifier: NCT00000462     History of Changes
Other Study ID Numbers: 51
U01HL038610 ( U.S. NIH Grant/Contract )
Study First Received: October 27, 1999
Last Updated: May 12, 2016

Additional relevant MeSH terms:
Diabetes Mellitus
Cardiovascular Diseases
Heart Diseases
Coronary Disease
Coronary Artery Disease
Myocardial Ischemia
Angina Pectoris
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Pathologic Processes
Vascular Diseases
Arterial Occlusive Diseases
Chest Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on August 23, 2017