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Comparison of Buprenorphine and Methadone - 3

This study has been completed.
Washington D.C. Veterans Affairs Medical Center
Information provided by:
National Institute on Drug Abuse (NIDA) Identifier:
First received: September 20, 1999
Last updated: January 30, 2017
Last verified: December 2002
The purpose of this study is to compare agonist and antagonist profile associated with buprenorphine vs. methadone during opiate withdrawal.

Condition Intervention Phase
Opioid-Related Disorders
Drug: Buprenorphine
Phase 2

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Pharmacological Comparison of Buprenorphine and Methadone

Resource links provided by NLM:

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Withdrawal severity
  • Opiate agonist symptoms

Estimated Enrollment: 0
Actual Study Start Date: December 1, 2002
Study Completion Date: January 15, 2005
Primary Completion Date: November 1, 2004 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   23 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
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Please refer to this study by its identifier: NCT00000334

United States, District of Columbia
Washington DC VA
Washington, District of Columbia, United States, 20422
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Washington D.C. Veterans Affairs Medical Center
Principal Investigator: Steven Deutsch, M.D. Washington D.C. Veterans Affairs Medical Center
  More Information Identifier: NCT00000334     History of Changes
Other Study ID Numbers: NIDA-3-0009-3
Study First Received: September 20, 1999
Last Updated: January 30, 2017

Additional relevant MeSH terms:
Opioid-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Analgesics, Opioid
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Antitussive Agents
Respiratory System Agents
Narcotic Antagonists processed this record on May 25, 2017