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Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2

This study has been completed.
Johns Hopkins University
Information provided by:
National Institute on Drug Abuse (NIDA) Identifier:
First received: September 20, 1999
Last updated: November 1, 2016
Last verified: August 1996
The purpose of this study is to determine the density of DA transporters during prolonged cocaine abuse and during withdrawal from cocaine use. This aim will test the hypothesis that DA transporters are altered by cocaine abuse and reestablished during withdrawal.

Condition Intervention Phase
Cocaine-Related Disorders
Drug: Cocaine
Phase 1

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Human Dopamine Transported Imaging in Cocaine Abuse: 2

Resource links provided by NLM:

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Psychological effects
  • Effects of investigational drug
  • Physiological changes in: heart rate and blood pre

Estimated Enrollment: 0
Study Start Date: August 1996
Estimated Study Completion Date: December 2001

Ages Eligible for Study:   21 Years to 45 Years   (Adult)
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
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Please refer to this study by its identifier: NCT00000316

United States, Maryland
Johns Hopkins University
Baltimore, Maryland, United States, 21287
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Johns Hopkins University
Principal Investigator: Dean Wong, M.D., Ph.D. Johns Hopkins University
  More Information Identifier: NCT00000316     History of Changes
Other Study ID Numbers: NIDA-09482-2  R01-09482-2 
Study First Received: September 20, 1999
Last Updated: November 1, 2016
Health Authority: United States: Federal Government

Keywords provided by National Institute on Drug Abuse (NIDA):
cocaine dependence

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Anesthetics, Local
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents
Cardiotonic Agents
Autonomic Agents
Protective Agents processed this record on December 09, 2016