Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Alterations in Serotonergic Functions in Cocaine Addicts - 1

This study has been completed.
VA Office of Research and Development
Information provided by:
National Institute on Drug Abuse (NIDA) Identifier:
First received: September 20, 1999
Last updated: June 23, 2005
Last verified: December 2002
The purpose of this study is to evaluate alterations in the serotonergic system in cocaine addicts and attempt to dissociate changes secondary to cocaine use from those associated with premorbid characteristics.

Condition Intervention Phase
Cocaine-Related Disorders
Drug: M-CPP
Phase 1

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Alterations in Serotonergic Functions in Cocaine Addicts

Resource links provided by NLM:

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Side effects
  • Neuroendocrine changes
  • Psychological changes
  • Craving

Estimated Enrollment: 0

Ages Eligible for Study:   25 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Please contact site for information.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00000312

United States, New York
VA Medical Center
Brooklyn, New York, United States, 11209
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
VA Office of Research and Development
Principal Investigator: Laure Buydens-Branchey, M.D. VA Office of Research and Development
  More Information

Biological Psychiatry (in press) The. AM. Int. on Addictions (in press) Identifier: NCT00000312     History of Changes
Other Study ID Numbers: NIDA-09468-1
Study First Received: September 20, 1999
Last Updated: June 23, 2005

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Anesthetics, Local
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents processed this record on April 28, 2017