Study Comparing Liquid and Tablet Buprenorphine Formulations - 5
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The purpose of this study is to compare liquid and tablet buprenorphine formulations.
Condition or disease
Participants were inducted on either liquid or tablet buprenorphine, in a double-blind, double-dummy manner. They each reached a steady state by the second week, and were scheduled to have blood draws in weeks 3, 4, 7, 8, 11, 12, 15, and 16.
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Layout table for eligibility information
Ages Eligible for Study:
21 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
M/F ages 21-50. Opiate dependence according to DSM-IV criteria. Currently enrolled in the outpatient protocol comparing liquid and tablet formulations of Buprenorphine. Agreeable to conditions of study and signed informed consent.
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.