Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13
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ClinicalTrials.gov Identifier: NCT00000261 |
Recruitment Status
:
Completed
First Posted
: September 21, 1999
Last Update Posted
: May 27, 2015
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Alcohol-Related Disorders Opioid-Related Disorders Substance-Related Disorders | Drug: 30% Nitrous oxide Other: Placebo Drug: 0.2% sevoflurane Drug: 0.4% sevoflurane Drug: 0.6% sevoflurane | Phase 2 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 14 participants |
Intervention Model: | Single Group Assignment |
Masking: | Double (Participant, Care Provider) |
Official Title: | Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide |
Study Start Date : | November 1997 |
Actual Primary Completion Date : | October 1998 |
Actual Study Completion Date : | October 1998 |
Arm | Intervention/treatment |
---|---|
Experimental: Moderate drinking adults |
Drug: 30% Nitrous oxide
Other: Placebo
No drug (100% oxygen)
Drug: 0.2% sevoflurane
Drug: 0.4% sevoflurane
Drug: 0.6% sevoflurane
|
- Mood [ Time Frame: Baseline, inhalation, recovery ]
- Psychomotor performance [ Time Frame: Baseline, inhalation, recovery ]
- Choice of drug vs placebo [ Time Frame: After placebo and drug in each session ]

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Ages Eligible for Study: | Child, Adult, Senior |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000261
United States, Illinois | |
University of Chicago, Anesthesia & Critical Care | |
Chicago, Illinois, United States, 60637 |
Principal Investigator: | James Zacny, Ph.D. | University of Chicago |
Responsible Party: | University of Chicago |
ClinicalTrials.gov Identifier: | NCT00000261 History of Changes |
Other Study ID Numbers: |
NIDA-08391-13 R01DA008391 ( U.S. NIH Grant/Contract ) R01-08391-13 |
First Posted: | September 21, 1999 Key Record Dates |
Last Update Posted: | May 27, 2015 |
Last Verified: | May 2015 |
Keywords provided by University of Chicago:
nitrous oxide sevoflurane ethanol subjective effects healthy volunteer |
Additional relevant MeSH terms:
Disease Substance-Related Disorders Opioid-Related Disorders Alcohol-Related Disorders Pathologic Processes Chemically-Induced Disorders Mental Disorders Sevoflurane Nitrous Oxide Platelet Aggregation Inhibitors |
Anesthetics, Inhalation Anesthetics, General Anesthetics Central Nervous System Depressants Physiological Effects of Drugs Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents |