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Carbamazepine Treatment of Cocaine Dependence - 1

This study has been completed.
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
Medical University of South Carolina Identifier:
First received: September 20, 1999
Last updated: October 8, 2015
Last verified: July 1996
The purpose of this study is to compare the efficacy of carbamazepine in treatment of cocaine-dependence in patients with affective disorders.

Condition Intervention Phase
Cocaine-Related Disorders
Substance-Related Disorders
Drug: Carbamazepine
Phase 2

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Carbamazepine Treatment of Cocaine Dependence

Resource links provided by NLM:

Further study details as provided by Medical University of South Carolina:

Primary Outcome Measures:
  • Severity addiction
  • Amount of drug use
  • Affective stability
  • Medication compliance

Estimated Enrollment: 0
Study Start Date: October 1992

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
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Please refer to this study by its identifier: NCT00000242

United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425 742
Sponsors and Collaborators
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)
Principal Investigator: Kathleen Brady, Ph.D. Medical University of South Carolina
  More Information

(1) Brady KT et. al. Features of cocaine dependence with concurrent alcohol abuse. Drug and Alcohol Depend. 1995, 39(1):69-71. (2) Brady KT et. al. Personality disorder and assault history in substance-dependent individuals. Am J on Addictions. 1995, 4(4):306-312. (3) Dansky et. al. Use of self-report measures of crime-related posttraumatic stress disorder with substance use disordered patients. Journal of Substance Abuse Treatment. (in press). (4) Sonne an Presentation at CPDD meeting, 1996.

Responsible Party: Medical University of South Carolina Identifier: NCT00000242     History of Changes
Other Study ID Numbers: NIDA-07761-1
R29DA007761 ( US NIH Grant/Contract Award Number )
Study First Received: September 20, 1999
Last Updated: October 8, 2015

Keywords provided by Medical University of South Carolina:
Substance Abuse

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Pathologic Processes
Chemically-Induced Disorders
Mental Disorders
Anesthetics, Local
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents
Antimanic Agents
Tranquilizing Agents
Psychotropic Drugs
Analgesics, Non-Narcotic
Cytochrome P-450 CYP3A Inducers
Cytochrome P-450 Enzyme Inducers processed this record on March 23, 2017