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Neurobiology of Opioid Dependence: 4 - 4

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00000195
Recruitment Status : Withdrawn
First Posted : September 21, 1999
Last Update Posted : May 6, 2016
Sponsor:
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
Yale University

Study Description
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Brief Summary:
The purpose of this study is to determine the effect of chronic naltrexone pre-treatment on the response to yohimbine in healthy volunteers.

Condition or disease Intervention/treatment Phase
Opioid-Related Disorders Drug: Naltrexone Phase 2

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Intervention Model: Crossover Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Neurobiology of Opioid Dependence: 4
Study Start Date : January 1993
Actual Primary Completion Date : January 1998
Actual Study Completion Date : January 1998

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Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. Behavioral, physiological, neuroendocrine response to yohimine

Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
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Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000195


Locations
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United States, Connecticut
VA Connecticut Healthcare System
New Haven, Connecticut, United States, 06519
Sponsors and Collaborators
Yale University
National Institute on Drug Abuse (NIDA)
Investigators
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Principal Investigator: Marc I Rosen, M.D. VA Connecticut Healthcare System
More Information
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Responsible Party: Yale University
ClinicalTrials.gov Identifier: NCT00000195    
Other Study ID Numbers: NIDA-00191-4
K20DA000191 ( U.S. NIH Grant/Contract )
K20-00191-4
First Posted: September 21, 1999    Key Record Dates
Last Update Posted: May 6, 2016
Last Verified: August 2015
Keywords provided by Yale University:
opioid disorders
Additional relevant MeSH terms:
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Opioid-Related Disorders
Narcotic-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Naltrexone
 Alcohol Deterrents
Narcotic Antagonists
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents